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Research Articles

Mastering SPR Reference Channel Strategies: A Comprehensive Guide to Drift Compensation and Data Quality

This article provides a complete guide to Surface Plasmon Resonance (SPR) reference channel strategies for effective baseline drift compensation.

Isaac Henderson
Dec 02, 2025

SPR Baseline Drift Rates: A Comprehensive Guide to Sensor Chip Selection and Optimization

This article provides researchers, scientists, and drug development professionals with a detailed analysis of Surface Plasmon Resonance (SPR) baseline drift rates across different sensor chips.

Naomi Price
Dec 02, 2025

SPR Drift Correction Algorithms: A Comprehensive Guide from Foundations to Advanced Applications

This article provides a systematic comparison of Surface Plasmon Resonance (SPR) drift correction algorithms, essential for ensuring data accuracy in biomolecular interaction analysis.

Addison Parker
Dec 02, 2025

Validating SPR Kinetic Data Despite Unstable Baselines: A Troubleshooting and Optimization Guide

Unstable baselines in Surface Plasmon Resonance (SPR) experiments pose a significant challenge, potentially compromising the accuracy of kinetic data.

Brooklyn Rose
Dec 02, 2025

Mastering Baseline Stability: A Comprehensive Guide to Evaluating and Optimizing SPR Instrument Performance

This article provides researchers, scientists, and drug development professionals with a complete framework for evaluating Surface Plasmon Resonance (SPR) instrument performance, with a dedicated focus on understanding, troubleshooting, and minimizing...

Jaxon Cox
Dec 02, 2025

SPR Baseline Stability: A Comparative Analysis of Biacore CM5 and XanTec CMD500M Sensor Chips

This article provides a comprehensive analysis for researchers and drug development professionals on the baseline stability and performance equivalence of the Biacore CM5 optical chip and its sanction-driven analogue, the...

Aaliyah Murphy
Dec 02, 2025

Mastering Drift Correction in SPR Kinetics: From Foundations to Advanced Applications

This article provides a comprehensive guide to identifying, troubleshooting, and correcting for baseline drift in Surface Plasmon Resonance (SPR) kinetic analysis.

Madelyn Parker
Dec 02, 2025

Stable SPR Baselines: A Complete Guide to Fluidic System Maintenance and Troubleshooting

This guide provides researchers, scientists, and drug development professionals with a comprehensive framework for achieving and maintaining stable baselines in Surface Plasmon Resonance (SPR) systems.

Joshua Mitchell
Dec 02, 2025

Preventing SPR Baseline Drift: A Complete Guide to Sensor Chip Storage and Handling

This article provides a comprehensive guide for researchers and drug development professionals on preventing baseline drift in Surface Plasmon Resonance (SPR) experiments.

Mason Cooper
Dec 02, 2025

Optimizing Buffer Conditions to Minimize SPR Drift: A Practical Guide for Robust Biomolecular Interaction Analysis

Surface Plasmon Resonance (SPR) is a powerful, label-free technique for real-time biomolecular interaction analysis, but its data quality is highly susceptible to baseline drift, often stemming from suboptimal buffer conditions.

Olivia Bennett
Dec 02, 2025

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